Author Archives: Alice Melao

Vyndaqel Is Safe, Effective for People with TTR-FAP, Review Study Suggests

Treatment with Vyndaqel (tafamidis) is a safe, non-invasive way to delay neurologic progression of transthyretin familial amyloid polyneuropathy (TTR-FAP), and preserves patients’ nutritional status and quality of life, a review study shows. The study, “Tafamidis, a Noninvasive Therapy for Delaying Transthyretin Familial Amyloid Polyneuropathy: Systematic Review…

Tegsedi and Onpattro May Ably Treat FAP, But Are Overpriced, ICER Reports

Prices for Tegsedi (inotersen) and Onpattro (patisiran) far exceed  thresholds for cost-effectiveness, despite their likely health benefits to people with hereditary transthyretin amyloidosis (hATTR) and their families, a report by a nonprofit group that analyzes U.S. treatment costs states. It recommended that the pharmaceutical companies marketing…

Rare Case of FAP and Mitochondrial Disease Reported in Study

The rare case of a patient in Italy who had familial amyloid poyneuropathy (FAP) in addition to mitochondrial disease was described in a report published in the journal Amyloid. The report was titled “Progressive axonal polyneuropathy in a mitochondrial disorder: an uncommon association with familial amyloid neuropathy.”…

Sudoscan, Test of Sweat Gland Function, Reliable in Assessing Peripheral Neuropathies, Study Reports

Evaluating the activity of sweat glands provides valuable information to assess peripheral nerve cell damage and help diagnose nerve diseases known as peripheral neuropathies, which includes familial amyloid polyneuropathy (FAP), a study reports. In particular, in comparing different approaches, researchers found that Impeto Medical’s noninvasive device Sudoscan appeared to…