Cathepsin E Implicated in Immune Dysfunction in FAP, May Be Biomarker, Mouse Study Suggests

The protein cathepsin E — known for regulating immune system cells — may be a potential biomarker for familial amyloid polyneuropathy (FAP), a study suggests. Specifically, researchers found that the protein was present at comparatively low levels in the macrophages — a type of immune cells —…

Taiwanese Team Develops Mouse Model That Displays the Early Stages of Human FAP

A new mouse model capable of displaying the early symptoms of familial amyloid polyneuropathy may help researchers understand mechanisms underlying the disease and test therapies that focus on its initial stages. The Taiwanese team that created the model wrote about it in the journal Neuropathology and Applied Neurobiology. The…