Eye involvement can become common over time in people with hereditary transthyretin amyloidosis (hATTR), a group of disorders that includes familial amyloid polyneuropathy (FAP), a study from Spain reported. Researchers also noted that symptoms affecting the eyes are often slower to develop than others due to this disease. As…
Members of a Chinese family carrying a rare gene mutation causing familial amyloid polyneuropathy (FAP) experienced abnormal protein deposits in the eye — manifesting as “floaters” — before having any other noticeable disease symptoms, a case series reported. Such protein deposits can lead to functional abnormalities of the retina,…
Familial amyloid polyneuropathy (FAP) is a disorder in which abnormal clumps of proteins called TTR amyloids accumulate in tissues and organs, interfering with their function. The aqueous humor of the eyes is one place where TTR amyloids accumulate. This is the jellylike substance that makes up most…