FAP Patients with Val30Met Mutation Exhibit Differences in Japan, Study Finds

Familial amyloid polyneuropathy patients with the Val30Met mutation differ in clinical symptoms, gene variants, and age of disease onset between endemic (where the disease is common) and non-endemic areas of Japan, a study reveals. In the study, “Origin of sporadic late-onset hereditary ATTR Val30Met amyloidosis in…

Portugal Has Highest Prevalence of TTR-FAP, but Rate of New Cases Decreasing, Study Finds

Portugal has the highest prevalence of transthyretin familial amyloid polyneuropathy (TTR-FAP) to date, although the number of new cases is decreasing, data from a national epidemiological study shows. Cases of late-onset disease are also increasing, with more patients developing their first symptoms at the age of 50 or older.